MISSION DISTRICT. This spacious establishment offers both globally inspired tapas and a selection of wines that is similarly far-reaching. Ahi tartare tacos and Vietnamese spring rolls hint at the food options, and reasonable prices make it easy to share a variety of dishes. The large wine list is available by the glass, flight, and half-bottle ­ treat yourself to Spanish reds, German whites, and a host of Californian vintages. While you sip, enjoy Andalu's upbeat ambience and clean-lined decor.

RUSSIAN HILL. Favored by locals, this tiny wine bar can be a tight fit, especially on weekends, but its selection is so good that folks can't pass it by. A few bar stools and a couple of leather love seats comprise the coveted handful of perches, and you'll often find people milling about before they head to dinner. Dozens of wines are available by the glass or bottle, and lots of regulars swear by the sake cocktails ­ not too sweet, not too overpowering. A cheese plate provides a foil to the alcohol, and a nearby sushi place even delivers to your seat.

CIVIC CENTER. Spare and sleek in decor, Cav (even the superfluous "e" has been dropped ­ pronounce it "cahv") prefers to let richness manifest itself in wine and food. More than 300 labels represent the globe, dovetailing with a menu of international culinary intrigue. Nibble artisan cheeses or house-made charcuterie, or expand your horizons with a supply of scrumptious, flavor-packed tapas. Classy and unpretentious, Cav offers 40 varieties by the glass, and its focus on lesser-known wines lets you freely and fearlessly experiment. Great for a date or a friends' night out.

HAYES VALLEY. Intimate and atmospheric, this European-styled establishment captivates visitors with its unmistakable charm. Metallic furnishings, ambient lighting and a secluded area in the back help the cause, as does intriguing original art, which changes monthly. French and Californian wines are prominent, but vintages hail from around the world, and selections are available by the glass or bottle. Accompany your favorite with a savory snack of cheese, caviar or olives, and relax in contented pleasure. Located behind Zuni Cafe.

MARINA DISTRICT. Boasting an 800-bottle collection, an appealing interior, a menu of tasty small plates, and a playful sense of itself that occasionally tends towards the overindulgent, Nectar does a brisk business, especially on weekends. The place features a bar, a lounge, and dining space, treating patrons to leisurely, wine-centered excursions. Cleverly named flights allow you to compare vintages; other options let you sip by the glass or by the taste. The menu offers sweet and savory dishes, including Moroccan spiced lamb, roasted foie gras, crisp-fried sardine filets, and Meyer lemon and olive oil cupcakes.